Janssen-Cilag Ltd

50 - 100 Holmers Farm Way, High Wycombe, Bucks, HP12 4EG
Telephone: +44 (0)1494 567 567
Fax: +44 (0)1494 567 568
WWW: http://www.janssen-cilag.co.uk
Medical Information Direct Line: +44 (0)800 731 8450
Medical Information e-mail: medinfo@janssen-cilag.co.uk
Customer Care direct line: +44 (0)800 731 5550
Summary of Product Characteristics last updated on the eMC: 03/11/2009
SPC Sporanox -Pulse

When a pharmaceutical company changes an SPC or PIL, a new version is published on the eMC. For each version, we show the dates it was published on the eMC and the reasons for change.

Updated on 03/11/2009 and displayed until Current
Reasons for adding or updating:
  • Change to section 1 -Name of the Medicinal product
  • Change to section 4.4 - Special warnings and precautions for Use
  • Change to section 4.8 - Undesirable Effects
  • Change to section 10 date of revision of the text
Date of revision of text on the SPC:   23-Oct-2009
Legal Category:   POM
Black Triangle (CHM):   NO

Free-text change information supplied by the pharmaceutical company



1.             Trade Name of the Medicinal Product

 

SporanoxPORANOX® -Pulse

 

4.4.         Special Warnings and Precautions for Use

 

Addition of hearing loss warning

4.8.         Undesirable Effects

 

Complete section has been re-worded 

10.          Date of (Partial) Revision of the Text

 

Changed from April 2009 to 23 October 2009

Updated on 20/04/2009 and displayed until 03/11/2009
Reasons for adding or updating:
  • Change to section 4.4 - Special warnings and precautions for Use
  • Change to section 10 date of revision of the text
Date of revision of text on the SPC:   01-Apr-2009
Legal Category:   POM
Black Triangle (CHM):   NO

Free-text change information supplied by the pharmaceutical company



Change to section 4.4 Special Warnings and Precautions for Use

Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Change to section 10 Date of Revision of the Text

Amended to ‘April 2009’

 

Updated on 18/09/2008 and displayed until 20/04/2009
Reasons for adding or updating:
  • Change to section 7 - Marketing Authorisation Holder
  • Change to section 10 date of revision of the text
Date of revision of text on the SPC:   01-Sep-2008
Legal Category:   POM
Black Triangle (CHM):   NO

Free-text change information supplied by the pharmaceutical company

Change to section 7 - New Company address
Change to section 10 - September 2008
Updated on 23/07/2008 and displayed until 18/09/2008
Reasons for adding or updating:
  • Change to section 6. 4 - Special Precautions for Storage
  • Change to section 10 date of revision of the text
Date of revision of text on the SPC:   01-Jul-2008
Legal Category:   POM
Black Triangle (CHM):   NO

Free-text change information supplied by the pharmaceutical company



Change to section 6.4 – Special Precautions for Storage

Store below 30C

X

Change to section 10 – Date of revision of the text

July 2008

Updated on 18/01/2008 and displayed until 23/07/2008
Reasons for adding or updating:
  • Change to section 4.1 - Therapeutic indications
  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for Use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 4.6 - Pregnancy and Lactation
  • Change to section 5.1 - Pharmacodynamic Properties
  • Change to section 5.2 - Pharmacokinetic Properties
  • Change to section 5.3 - Preclinical Safety Data
  • Change to section 10 date of revision of the text
Date of revision of text on the SPC:   01/2008
Legal Category:   POM
Black Triangle (CHM):   NO

Free-text change information supplied by the pharmaceutical company

Change to section 4.1 – Therapeutic Indications

Treatment of aspergillosis and candidosis

Treatment of cryptococcosis (including cryptococcal meningitis): in immunocompromised patients with cryptococcosis and in all patients with cryptococcosis of the central nervous system.Maintenance therapy in AIDS patients to prevent relapse of underlying fungal infection.

Change to section 4.2 – Posology and |Method of Administration

1 The duration of treatment should be adjusted depending on the clinical response.

Additional statements on use in children and elderly, renal and hepatic impairment

Change to section 4.3 – Contra-indications

New layout and addition of Eletriptan and NIsoldipine

Change to section 4.4 – Special Warnings and Precautions for Use

New layout and addition of warnings to children and Elderly and renal and hepatic effects

Change to section 4.5 –Interaction with other medicinal products and other forms of interaction

New layout and addition of Eletriptan and Nisoldipine

Change to section 4.6 – Pregnancy and Lactation

New layout and new data.

Change to section 5.1 - Pharmacodynamic properties

All new information

 

Change to section 5.2 - Pharmacokinetic properties

New layout and new information on special populations

Change to section 5.3 - Preclinical Safety Data

All new information

Change to section 10 – Date of revision of the text

January 2008

Updated on 24/08/2007 and displayed until 18/01/2008
Reasons for adding or updating:
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
Date of revision of text on the SPC:   08/2007
Legal Category:   POM
Black Triangle (CHM):   NO

Free-text change information supplied by the pharmaceutical company

Change to section 4.5 –Interaction with other medicinal products and other forms of interaction

Addition of interaction with Fluticasone

Change to section 10 – Date of revision of the text

August 2007

Updated on 21/09/2004 and displayed until 24/08/2007
Reasons for adding or updating:
  • Change to section 4.4 - Special Warnings and Precautions for Use
  • Change to section 4.8 - Undesirable Effects
  • Change to section 10 (date of (partial) revision of the text
Updated on 02/09/2004 and displayed until 21/09/2004
Reasons for adding or updating:
  • Change to section 4.4 - Special Warnings and Precautions for Use
  • Change to section 4.8 - Undesirable Effects
  • Change to section 10 (date of (partial) revision of the text
Updated on 10/10/2001 and displayed until 02/09/2004
Reasons for adding or updating:
  • Change to section 4.4 - Special Warnings and Precautions for Use
Updated on 24/08/2001 and displayed until 10/10/2001
Reasons for adding or updating:
  • Transferred from eMC version 1
Updated on 23/08/2001 and displayed until 24/08/2001
Reasons for adding or updating:
  • Transferred from eMC version 1
Updated on 24/02/2000 and displayed until 23/08/2001
Reasons for adding or updating:
  • No reasons supplied
Updated on 06/09/1999 and displayed until 24/02/2000
Reasons for adding or updating:
  • No reasons supplied

Active Ingredients/Generics

 
   itraconazole


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